Cell Culture Growth Factors and Hormones
Sigma Aldrich Fine Chemicals Biosciences Prostaglandin E2 | 363-24-6 | MFCD00077861 | 10mg
Prostaglandin E2 | Purity: 93% | 352.47 | 363-24-6 | MFCD00077861 | 10mg
United States Biological Corporation INTEGRIN ALPHAL BETA2 RECOMB
NC3364842 INTEGRIN ALPHAL BETA2 RECOMB
New England Biolabs, Inc. SOC Outgrowth Medium – 4 x 25 ml medium
Add SOC to freshly transformed E. coli cells and incubate for up to 1 hour before plating on selective media. 1X SOC Outgrowth Medium: 2% Vegetable Peptone 0.5% Yeast Extract 10 mM NaCl 2.5 mM KCl 10 mM MgCl2 10 mM MgSO4 20 mM Glucose.
Medchemexpress LLC Her3 protein, rat (HEK293, His) | >95.0% | 1 MG
Recombinant rat HER3 protein expressed in HEK293 mammalian cells with a C-terminal His tag, supplied lyophilized for research applications in signaling and interaction studies. The protein is glycosylated, displays an apparent molecular weight of approximately 85-115 kDa, and is provided with analytical documentation for quality control.
- Mammalian expression provides native glycosylation
- C-terminal His tag for purification and detection
- Apparent molecular weight ~85-115 kDa due to glycosylation
- Purity >95.0% by reducing SDS-PAGE
- Lyophilized from PBS (pH 7.4) for stability
- Store at -20°C; after reconstitution stable at 4°C for 1 week or -20°C long-term
- Datasheet, COA, and SDS available for quality and safety information
Medchemexpress LLC Recombinant human placental growth factor-2 (PLGF-2), mFc-tagged | 97.5% | 50 UG
Recombinant human placental growth factor-2 (PLGF-2) is provided as a purified, murine Fc-tagged protein expressed in HEK293 cells for in vitro research. It is suitable for studies of angiogenesis, endothelial cell signaling, and receptor-binding assays; follow the manufacturer datasheet for formulation and storage instructions.
- Expressed in HEK293 cells.
- C-terminal murine Fc fusion to aid stability and detection.
- Purified to 97.5%.
- Suitable for in vitro angiogenesis and receptor-binding studies.
- Supplied in a 50 μg format; consult datasheet for concentration and storage.
STEMCELL Technologies Human Recombinant FGF-16, Size: 10 µg
Fibroblast growth factor 16 (FGF-16) is a heparin-binding member of the FGF family. FGFs possess broad mitogenic and cell survival activities and are expressed during embryonic development. FGFs act primarily on cells of mesodermal and neuroectodermal origin to regulate diverse physiological functions including angiogenesis, cell growth, pattern formation, embryonic development, metabolic regulation, cell migration, and tissue repair (Goldfarb; Green et al.). In vitro, FGF-16 has been shown to promote the proliferation of brown adipocytes and in rat embryos it is predominantly expressed in these cells. FGF-16 has also been shown to play a critical role in embryonic heart development and is thought to play a cardioprotective role after birth (Hotta et al.; Lu et al.; Wang et al.).
STEMCELL Technologies Human Recombinant Persephin, Size: 20 µg
Persephin is a neurotrophic factor that belongs to the glial cell line-derived neurotrophic factor (GDNF) family. Persephin shares a large degree of structural similarity to GDNF, artemin, and neurturin, and has overall neuroprotective activity. Persephin signals through GRFα4 (glycosylphosphatidylinositol (GPI)-linked GDNF receptor family member) which signals through the receptor tyrosine kinase RET. Unlike GDNF and neurturin, persephin only promotes the growth and survival of central dopaminergic and motor neurons, but not peripheral neurons (Milbrandt et al.). In vitro, persephin only promotes survival of neurons that co-express GPI-linked GRFα4 and RET (Enokido et al.; Lindahl et al.). Mice lacking persephin showed increased cell death after cerebral ischemia, however administration of persephin before ischemia dramatically reduced neuronal cell death (Tomac et al.).
STEMCELL Technologies Human Recombinant PDGF-CC, Size: 50 µg
Use platelet-derived growth factor (PDGF) CC in stimulating coronary artery smooth muscle cell proliferation (Gilbertson et al. J Biol Chem, 2001) and tumorigenesis (Zwerner & May. Oncogene, 2001). The PDGF family has five heparin-binding members that assemble into four homodimers (PDGF-AA, PDGF-BB, PDGF-CC, and PDGF-DD) and one heterodimer (PDGF-AB) (Fretto et al. J Biol Chem, 1993; Li & Eriksson. Cytokine Growth Factor Rev, 2003) and signals through the receptor tyrosine kinases PDGFRα and PDGFRβ. PDGF is a potent mitogen for cells of mesenchymal origin and induces migration through signaling pathways involving MEK/ERK, EGFR, Src, and PI3K/AKT (Kim et al. Growth Factors, 2007). PDGF-CC is secreted as a latent growth factor and requires activation by proteolytic processing (Li & Eriksson). Human recombinant PDGF-CC from STEMCELL comes lyophilized with ≥ 95% purity; EC50 ≤ 1 ng/mL; endotoxin levels verified ≤ 0.2 EU/μg protein. Alternative names: PDGF, Platelet-derived growth factor.